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Open Source 3D DNA Origami

DNA origami is a powerful method for constructing DNA objects. It involves taking a long, single-stranded DNA backbone (usually about 7000 bases in length) and forcing it to adopt an arbitrary shape using hundreds of short, single-stranded DNA oligonucleotides (each usually 20 to 50 bases long).

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caDNAno is open-source software based on the Adobe AIR platform for design of three-dimensional DNA origami nanostructures. It was written with the goal of providing a fast and intuitive means to create and modify DNA origami designs. You can learn how to use it, download a copy of the program and some example designs, or even modify the source code.

The software makes heavy use of several fantastic open-source libraries and resources, especially Papervision3D for 3D rendering, Michael Baczynski‘s AS3 data structures and tutorials, the Tango Desktop Project for icons, and the Blueprint CSS framework for this website.

Features

  • No programming required
  • Integrated 2D and 3D interfaces
  • Visual cues to aid design process
  • Export formats: SVG, X3D, JSON
  • Platform independent
  • Open source (MIT license)


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