When you need to analyze a new network protocol for buffer overflows or similar weaknesses, the SPIKE is the tool of choice for professionals. While it requires a strong knowledge of C to use, it produces results second to none in the field. SPIKE is available for the Linux platform only.
Not all web applications are built in the same ways, and hence, many must be analyzed individually. SPIKE Proxy is a professional-grade tool for looking for application-level vulnerabilities in web applications. SPIKE Proxy covers the basics, such as SQL Injection and cross-site-scripting, but it’s completely open Python infrastructure allows advanced users to customize it for web applications that other tools fall apart on. SPIKE Proxy is available for Linux and Windows.